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Ask Dr. Stephan Moll

These questions have been submitted by folks on the mailing list and answered by Dr. Moll, Director of the Thrombophilia Program at the Carolina Cardiovascular Biology Center, Department of Medicine, Division of Hematology-Oncology, UNC Chapel Hill (North Carolina, USA). Why am I doing this?

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67. Dental work and factor V Leiden

Last Updated: 2/15/2004


Q: "My dentist refused to clean my teeth because I have factor V Leiden. Do you have anything published I can take to the dentist to show that it is o.k. to work on my teeth?"

A: Factor V Leiden is a very common variant of clotting factor V, present in ca. 5 % of the Caucasian population. While it slightly increases the risk for venous thromboembolism (4-7 fold for the heterozygous individual compared to people who do not have factor V Leiden), most individuals with FVLeiden never have any medical problems in their lifetime related to factor V Leiden. No special precautions need to be taken when doing dental work (teeth cleaning, extractions, root canals, etc.), unless patients are, for some reason, on blood thinners.

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